Cell transplantation for the treatment of spinal cord injury - bone marrow stromal cells and choroid plexus epithelial cells

Cell transplantation for the treatment of spinal cord injury – bone marrow stromal cells and choroid plexus epithelial cells

Transplantation of bone marrow stromal cells (BMSCs) enhanced the outgrowth of regenerating axons and promoted locomotor improvements of rats with spinal cord injury (SCI). BMSCs did not survive long-term, disappearing from the spinal cord within 2-3 weeks after transplantation. Astrocyte-devoid areas, in which no astrocytes or oligodendrocytes were found, formed at the epicenter of the lesion....

The future of bone marrow stromal cell transplantation for the treatment of spinal cord injury

Improvement of Spinal Cord Injury in Rat Model via Transplantation of Neural Stem Cells Derived From Bone Marrow

Abstract Background & Aims: Cell therapy is among the novel therapeutic methods effective in the treatment of spinal cord injuries. The aim of the present study was using neural stem cells (NSCs) in treating contusion spinal cord injury in rat model. Methods: Bone marrow stromal cells (BMSCs) were isolated from adult rats...

Transplanting P75-Suppressed Bone Marrow Stromal Cells Promotes Functional Behavior in a Rat Model of Spinal Cord Injury

Background: Bone marrow stromal cells (BMSC) have been successfully employed for movement deficit recovery in spinal cord injury (SCI) rat models. One of the unsettled problems in cell transplantation is the relative high proportion of cell death, specifically after neural differentiation. According to our previous studies, p75 receptor, known as the death receptor, is only expressed in BMSC in...

P41: Therapeutic Effect of Transplanting Neural Stem Cells Derived Bone Marrow Stromal Cells Using Bioactive Substance TNT, for Enhance Recovery from Spinal Cord Injury

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